Title : Nitrocatechol Derivatives of Chalcone as Inhibitors of Monoamine Oxidase and Catechol-O-Methyltransferase.

Pub. Date : 2018

PMID : 29697034






1 Functional Relationships(s)
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1 The chalcone class of compounds is well known to potently inhibit MAO-B, while nitrocatechol derivatives (e.g. tolcapone and entacapone) are clinically used COMT inhibitors. entacapone catechol-O-methyltransferase Homo sapiens