Title : A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension.

Pub. Date : 2018 Jul

PMID : 29677047






4 Functional Relationships(s)
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1 OBJECTIVES: Noradrenaline released from sympathetic nerves is rapidly inactivated via the action of the noradrenaline transporter (NET). Norepinephrine solute carrier family 6 member 2 Homo sapiens
2 OBJECTIVES: Noradrenaline released from sympathetic nerves is rapidly inactivated via the action of the noradrenaline transporter (NET). Norepinephrine solute carrier family 6 member 2 Homo sapiens
3 We aimed to determine whether a single nucleotide polymorphism (SNP) in the NET gene, rs7194256, was associated with blood pressure and plasma noradrenaline concentration in patients with resistant hypertension. Norepinephrine solute carrier family 6 member 2 Homo sapiens
4 CONCLUSION: A SNP in the NET gene in patients with resistant hypertension is associated with higher plasma noradrenaline concentration and elevated SBP. Norepinephrine solute carrier family 6 member 2 Homo sapiens