Title : Induced pluripotent stem cell-derived conditional medium promotes Leydig cell anti-apoptosis and proliferation via autophagy and Wnt/β-catenin pathway.

Pub. Date : 2018 Jul

PMID : 29667777






1 Functional Relationships(s)
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1 The results showed that iPS-CM significantly reduced H2 O2 -induced ILC apoptosis through down-regulation of autophagic and apoptotic proteins LC3-I/II, Beclin-1, P62, P53 and BAX as well as up-regulation of BCL-2, which could be inhibited by LY294002 (25 mumol/L). Hydrogen Peroxide tumor protein p53 Homo sapiens