Title : Antihypertensive and renal effects of cilazapril and their reversal by angiotensin in renovascular hypertensive rats.

Pub. Date : 1988 Apr

PMID : 2965632






3 Functional Relationships(s)
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1 Superimposed administration of either angiotensin II or angiotensin III during cilazapril infusion completely reversed the blood pressure and bilateral renal responses of cilazapril in both hypertensive and normotensive rats. Cilazapril angiotensinogen Rattus norvegicus
2 Superimposed administration of either angiotensin II or angiotensin III during cilazapril infusion completely reversed the blood pressure and bilateral renal responses of cilazapril in both hypertensive and normotensive rats. Cilazapril angiotensinogen Rattus norvegicus
3 These results indicate that cilazapril reduces arterial pressure and enhances renal excretion mainly via inhibition of angiotensin II and angiotensin III formation. Cilazapril angiotensinogen Rattus norvegicus