Pub. Date : 2018 Apr 18
PMID : 29643533
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Electrophoretic mobility shift assay (EMSA) was taken to investigate whether etoposide enhanced the binding of NF-kappaB to MICA/B gene promoter. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Similarly, NF-kappaB inhibitor PDTC also inhibited MICA/B mRNA and protein expressions induced by etoposide significantly when MCF-7 cells were incubated with PDTC at the concentrations of 10, 50 and 100 mumol/L (P<0.05), indicating that NF-kappaB was also involved in this process. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | Similarly, NF-kappaB inhibitor PDTC also inhibited MICA/B mRNA and protein expressions induced by etoposide significantly when MCF-7 cells were incubated with PDTC at the concentrations of 10, 50 and 100 mumol/L (P<0.05), indicating that NF-kappaB was also involved in this process. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | EMSA showed that the binding of NF-kappaB to MICA/B promoter enhanced in MCF-7 cells after etoposide treatment. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |