Pub. Date : 2018 Apr 10
PMID : 29642608
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Neuroprotective Effects of Four Phenylethanoid Glycosides on H2O2-Induced Apoptosis on PC12 Cells via the Nrf2/ARE Pathway. | Hydrogen Peroxide | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |
2 | PhGs pretreatment significantly suppressed H2O2-induced cytotoxicity in PC12 cells by triggering the nuclear translocation of Nrf2 and reversing the downregulated protein expression of heme oxygenase 1 (HO-1), NAD(P)H quinone oxidoreductase 1 (NQO1), glutamate cysteine ligase-catalytic subunit (GCLC), and glutamate-cysteine ligase modifier subunit (GCLM). | Hydrogen Peroxide | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |