Title : Effects of neuromedin B on steroidogenesis, cell proliferation and apoptosis in porcine Leydig cells.

Pub. Date : 2018 Jul

PMID : 29632025






1 Functional Relationships(s)
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1 NMBR was mainly expressed in the Leydig cells of porcine testes, and a specific dose of NMB significantly promoted the secretion of testosterone in the primary Leydig cells; moreover, NMB increased the expression of mRNA and/or proteins of NMBR and steroidogenic mediators (steroidogenic acute regulatory (STAR), CYP11A1, and HSD3B1) in the Leydig cells. Testosterone neuromedin B receptor Homo sapiens