Title : Influence of ABCB1 and CYP3A5 gene polymorphisms on pharmacokinetics of apixaban in patients with atrial fibrillation and acute stroke.

Pub. Date : 2018

PMID : 29606886






1 Functional Relationships(s)
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1 CYP3A isoenzyme group activity was evaluated by determining urinary concentration of endogenous substrate of the enzyme and its metabolite (6-beta-hydroxycortisol to cortisol ratio). Hydrocortisone cytochrome P450 family 3 subfamily A member 4 Homo sapiens