Title : Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.

Pub. Date : 2018

PMID : 29599817






1 Functional Relationships(s)
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1 The mRNA expression levels of GSK3beta and DKK1 in the WYHZTL formula and XAV-939-treated group were significantly higher than those in the BLM group, while Wnt1, beta-catenin, TCF4, cyclin D1, survivin, VEGF, CTGF, FN1, collagen I/III were decreased. XAV939 vascular endothelial growth factor A Mus musculus