Title : AZD5153, a novel BRD4 inhibitor, suppresses human thyroid carcinoma cell growth in vitro and in vivo.

Pub. Date : 2018 May 15

PMID : 29596834






2 Functional Relationships(s)
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1 BRD4-regulated proteins, including c-Myc, Bcl-2 and cyclin D1, were significantly downregulated following AZD5153 treatment in TPC-1 and primary cancer cells. AZD5153 BCL2 apoptosis regulator Homo sapiens
2 BRD4-dependent proteins, Myc, Bcl-2 and cyclin D1, were also downregulated in AZD5153-treated tumor tissues. AZD5153 BCL2 apoptosis regulator Homo sapiens