Title : Influence of acute promyelocytic leukemia therapeutic drugs on nuclear pore complex density and integrity.

Pub. Date : 2018 May 15

PMID : 29596829






2 Functional Relationships(s)
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1 Recent studies suggest that pharmacological concentrations of the APL therapeutic drugs, all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), affect post-mitotic nuclear import of the APL-associated oncoprotein PML/RARA. Tretinoin PML nuclear body scaffold Homo sapiens
2 Recent studies suggest that pharmacological concentrations of the APL therapeutic drugs, all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), affect post-mitotic nuclear import of the APL-associated oncoprotein PML/RARA. Tretinoin PML nuclear body scaffold Homo sapiens