Title : Itraconazole-Induced Inhibition on Human Esophageal Cancer Cell Growth Requires AMPK Activation.

Pub. Date : 2018 Jun

PMID : 29592879






1 Functional Relationships(s)
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1 Furthermore, AMPK activation by itraconazole induced multiple receptor tyrosine kinases (RTKs: EGFR, PDGFRalpha, and PDGFRbeta), lysosomal translocation, and degradation to inhibit downstream Akt activation. Itraconazole platelet derived growth factor receptor beta Homo sapiens