Title : Biguanides Metformin and Phenformin Generate Therapeutic Effects via AMP-Activated Protein Kinase/Extracellular-Regulated Kinase Pathways in an In Vitro Model of Graves' Orbitopathy.

Pub. Date : 2018 Apr

PMID : 29589999






1 Functional Relationships(s)
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1 The IL-1beta-induced hyaluronan production and mRNA expression of IL-6, cyclooxygenase-2, and intercellular adhesion molecule-1 were also significantly suppressed after metformin or phenformin co-treatment. Metformin interleukin 6 Homo sapiens