Title : Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine.

Pub. Date : 2018 Dec

PMID : 29569712






1 Functional Relationships(s)
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1 Induction of P-gp, CYP2C9, and decreased sofosbuvir exposure were successfully predicted by observed CYP3A induction. Sofosbuvir cytochrome P450 family 3 subfamily A member 4 Homo sapiens