Pub. Date : 2018 Apr
PMID : 29569540
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Leucine promotes differentiation of porcine myoblasts through the protein kinase B (Akt)/Forkhead box O1 signalling pathway. | Leucine | thymoma viral proto-oncogene 1 | Mus musculus |
2 | In addition, leucine increased the levels of phosphorylated Akt/Akt and phosphorylated Forkhead box O1 (P-FoxO1)/FoxO1, as well as decreased the protein level of FoxO1. | Leucine | thymoma viral proto-oncogene 1 | Mus musculus |
3 | In addition, leucine increased the levels of phosphorylated Akt/Akt and phosphorylated Forkhead box O1 (P-FoxO1)/FoxO1, as well as decreased the protein level of FoxO1. | Leucine | thymoma viral proto-oncogene 1 | Mus musculus |
4 | However, wortmannin, a specific repressor of PI3K/Akt signalling pathway, attenuated the positive role of leucine on porcine myoblast differentiation. | Leucine | thymoma viral proto-oncogene 1 | Mus musculus |
5 | Our results suggest that leucine promotes porcine myoblast differentiation through the Akt/FoxO1 signalling pathway. | Leucine | thymoma viral proto-oncogene 1 | Mus musculus |