Title : Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis.

Pub. Date : 2018 Apr

PMID : 29567797






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activity. Lipid A toll like receptor 4 Homo sapiens