Title : Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1.

Pub. Date : 2018

PMID : 29559849






2 Functional Relationships(s)
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1 Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens
2 In addition, functional assays revealed that circPVT1 knockdown by siRNA could weaken the resistance to doxorubicin and cisplatin of OS cells through decreasing the expression of classical drug resistance-related gene ABCB1. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens