Title : [Inhibitory effect and mechanism of platycodin D combined with imatinib on K562/R].

Pub. Date : 2018 Jan

PMID : 29552859






1 Functional Relationships(s)
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1 The results indicated that PD increased the sensitivity of drug-resistant cells to imatinib, and the inhibitory effect of PD combined with imatinib was significantly better than the single drug on cell proliferation, induction of apoptosis, inhibition of Bcr/abl protein and PI3K/AKT/mTOR signaling pathway. Imatinib Mesylate mechanistic target of rapamycin kinase Homo sapiens