Title : Paroxetine and Low-dose Risperidone Induce Serotonin 5-HT1A and Dopamine D2 Receptor Heteromerization in the Mouse Prefrontal Cortex.

Pub. Date : 2018 May 1

PMID : 29544901






4 Functional Relationships(s)
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1 Paroxetine and Low-dose Risperidone Induce Serotonin 5-HT1A and Dopamine D2 Receptor Heteromerization in the Mouse Prefrontal Cortex. Paroxetine 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
2 In the present study, we investigated 5-HT1A-D2 receptor heteromerization in mice treated acutely or chronically with paroxetine (10 mg/kg) or risperidone (0.05 mg/kg). Paroxetine 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
3 Chronic administration of paroxetine or risperidone increased the level of 5-HT1A-D2 receptor heteromers in the prefrontal cortex. Paroxetine 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
4 The obtained data indicate that the increase in 5-HT1A-D2 receptor heteromerization is a common molecular characteristic of paroxetine and low-dose risperidone treatment. Paroxetine 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus