Pub. Date : 2018 May 1
PMID : 29544901
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Paroxetine and Low-dose Risperidone Induce Serotonin 5-HT1A and Dopamine D2 Receptor Heteromerization in the Mouse Prefrontal Cortex. | Paroxetine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
2 | In the present study, we investigated 5-HT1A-D2 receptor heteromerization in mice treated acutely or chronically with paroxetine (10 mg/kg) or risperidone (0.05 mg/kg). | Paroxetine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
3 | Chronic administration of paroxetine or risperidone increased the level of 5-HT1A-D2 receptor heteromers in the prefrontal cortex. | Paroxetine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
4 | The obtained data indicate that the increase in 5-HT1A-D2 receptor heteromerization is a common molecular characteristic of paroxetine and low-dose risperidone treatment. | Paroxetine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |