Pub. Date : 2018 Apr
PMID : 29541178
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mechanism analysis demonstrated that Tunicamycin inhibited the protein kinase B (Akt) and nuclear factor-kappaB (NF-kappaB) signaling pathways, whilst Akt overexpression significantly cancelled out the Tunicamycin-inhibited growth and aggressiveness of breast cancer cells, as compared with control cells. | Tunicamycin | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Mechanism analysis demonstrated that Tunicamycin inhibited the protein kinase B (Akt) and nuclear factor-kappaB (NF-kappaB) signaling pathways, whilst Akt overexpression significantly cancelled out the Tunicamycin-inhibited growth and aggressiveness of breast cancer cells, as compared with control cells. | Tunicamycin | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | In conclusion, these results indicate that Tunicamycin may inhibit the growth and aggressiveness of breast cancer cells via regulation of the Akt/NF-kappaB signaling pathway. | Tunicamycin | thymoma viral proto-oncogene 1 | Mus musculus |