Title : Etoposide radiosensitizes p53-defective cholangiocarcinoma cell lines independent of their G2 checkpoint efficacies.

Pub. Date : 2018 Mar

PMID : 29541168






4 Functional Relationships(s)
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1 Etoposide radiosensitizes p53-defective cholangiocarcinoma cell lines independent of their G2 checkpoint efficacies. Etoposide tumor protein p53 Homo sapiens
2 The present study evaluated the radiosensitization potential of etoposide in p53-defective CCA KKU-M055 and KKU-M214 cell lines. Etoposide tumor protein p53 Homo sapiens
3 Treatment with etoposide enhanced the responsiveness of two p53-defective CCA cell lines to radiation independent of G2 checkpoint function. Etoposide tumor protein p53 Homo sapiens
4 These findings indicate that etoposide could be used as a radiation sensitizer for p53-defective tumors, independent of the function of G2 checkpoint. Etoposide tumor protein p53 Homo sapiens