Pub. Date : 2018 May 5
PMID : 29530563
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For instance, the commonly-used solubilizing agent polyethylene glycol 400 (PEG 400) exhibits a sex-specific effect on the bioavailability of ranitidine in both humans and rats, mediated by the efflux transporter P-glycoprotein (P-gp). | Ranitidine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 2 | For instance, the commonly-used solubilizing agent polyethylene glycol 400 (PEG 400) exhibits a sex-specific effect on the bioavailability of ranitidine in both humans and rats, mediated by the efflux transporter P-glycoprotein (P-gp). | Ranitidine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 3 | In addition, while the P-gp inhibitor CsA increased the intestinal uptake of ranitidine in both male and female rats, a greater extent of intestinal transport modulation was observed in males compared to females. | Ranitidine | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |