Title : Recombinant human IgE.

Pub. Date : 1987

PMID : 2952601






1 Functional Relationships(s)
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1 The gene for a human epsilon chain Fc fragment has been cloned and expressed at a high level in Escherichia coli, and its biological activity in binding to the high-affinity receptors on mast cells and basophils and mediating histamine release has been examined in a variety of assays, including the inhibition of passive cutaneous anaphylaxis in human skin, which was induced by ragweed immunoglobulin IgE antibody and antigen. Histamine immunoglobulin heavy constant epsilon Homo sapiens