Title : Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells.

Pub. Date : 2018 Jun

PMID : 29524540






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BACKGROUND: Myeloperoxidase (MPO) generates hypochlorous acid (HOCl) during inflammation and infection. Hypochlorous Acid myeloperoxidase Homo sapiens
2 BACKGROUND: Myeloperoxidase (MPO) generates hypochlorous acid (HOCl) during inflammation and infection. Hypochlorous Acid myeloperoxidase Homo sapiens
3 BACKGROUND: Myeloperoxidase (MPO) generates hypochlorous acid (HOCl) during inflammation and infection. Hypochlorous Acid myeloperoxidase Homo sapiens
4 BACKGROUND: Myeloperoxidase (MPO) generates hypochlorous acid (HOCl) during inflammation and infection. Hypochlorous Acid myeloperoxidase Homo sapiens
5 However, the action of SDG and its synthetic version, LGM2605, on MPO-catalyzed generation of HOCl is unknown. Hypochlorous Acid myeloperoxidase Homo sapiens
6 METHODS: MPO activity was determined fluorometrically using hypochlorite-specific 3"-(p-aminophenyl) fluorescein (APF). Hypochlorous Acid myeloperoxidase Homo sapiens