Pub. Date : 2018
PMID : 29520229
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tacrolimus Reverses UVB Irradiation-Induced Epidermal Langerhans Cell Reduction by Inhibiting TNF-alpha Secretion in Keratinocytes via Regulation of NF-kappaB/p65. | Tacrolimus | tumor necrosis factor | Homo sapiens |
| 2 | Tacrolimus significantly inhibited UVB irradiation-induced tumor necrosis factor-alpha (TNF-alpha) and nuclear factor kappa B (NF-kappaB)/p65 mRNA and protein expression in HaCaT cells. | Tacrolimus | tumor necrosis factor | Homo sapiens |
| 3 | Tacrolimus significantly inhibited UVB irradiation-induced tumor necrosis factor-alpha (TNF-alpha) and nuclear factor kappa B (NF-kappaB)/p65 mRNA and protein expression in HaCaT cells. | Tacrolimus | tumor necrosis factor | Homo sapiens |
| 4 | Tacrolimus also significantly inhibited high-dose UVB irradiation-induced TNF-alpha expression in cultured tissues. | Tacrolimus | tumor necrosis factor | Homo sapiens |
| 5 | Conclusion: Topical tacrolimus 0.03% could reverse UVB irradiation-induced epidermal LC reduction by inhibiting TNF-alpha secretion in keratinocytes via regulation of NF-kappaB/p65. | Tacrolimus | tumor necrosis factor | Homo sapiens |