Title : Entrainment of the Circadian Clock in Neural Stem Cells by Epidermal Growth Factor is Closely Associated with ERK1/2-mediated Induction of Multiple Clock-related Genes.

Pub. Date : 2018 May 21

PMID : 29518531






1 Functional Relationships(s)
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1 Pretreatment with the MEK1/2 inhibitor U0126 significantly suppressed the acute induction of Per2, Dec1, and Noct by EGF and also abolished the EGF-induced phase shift of the PER2::LUCIFERASE rhythm in NSCs. U 0126 mitogen-activated protein kinase kinase 1 Mus musculus