Pub. Date : 2018 Jan-Mar
PMID : 29516929
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The proportion of TOP2A-positive cancer cells was significantly higher among anthracycline responders than among nonresponders in HR-negative cancer (15.4% +-17.5% vs. 2.0% +- 2.4%, respectively, P = 0.048), whereas TOP2A and TIMP-1 expression statuses did not differ in HR-positive cancer. | Anthracyclines | DNA topoisomerase II alpha | Homo sapiens |
| 2 | The proportion of TOP2A-positive cancer cells was significantly higher among anthracycline responders than among nonresponders in HR-negative cancer (15.4% +-17.5% vs. 2.0% +- 2.4%, respectively, P = 0.048), whereas TOP2A and TIMP-1 expression statuses did not differ in HR-positive cancer. | Anthracyclines | DNA topoisomerase II alpha | Homo sapiens |
| 3 | Anthracycline responders showed a trend to have a higher proportion of patients with either >=5% TOP2A-positive cancer cells or <=20% TIMP-1-positive cancer cells compared to nonresponders (86.7% vs. 61.5%, respectively, P = 0.066). | Anthracyclines | DNA topoisomerase II alpha | Homo sapiens |