Title : Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient.

Pub. Date : 2018 Jul

PMID : 29514873






2 Functional Relationships(s)
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1 Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. Arachidonic Acid fatty acid desaturase 1 Homo sapiens
2 Hypothesis-neutral comparison of the 33 fractions showed that the most significant genetic association at the FADS1/2/3 locus was with fraction of arachidonic acid (AA) at SNP rs174556, with a very large per major allele effect size of 17% higher breast milk AA level. Arachidonic Acid fatty acid desaturase 1 Homo sapiens