Title : Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy.

Pub. Date : 2018 Apr

PMID : 29502024






1 Functional Relationships(s)
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1 Herein we report the synthesis of a new series of aromatic sulfamates designed considering the sulfonamide COX-2 selective inhibitors celecoxib and valdecoxib as lead compounds. valdecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens