Title : Myeloperoxidase-catalyzed oxidation of cyanide to cyanate: A potential carbamylation route involved in the formation of atherosclerotic plaques?

Pub. Date : 2018 Apr 27

PMID : 29496995






2 Functional Relationships(s)
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1 Moreover, we present two further pathways of carbamylation that involve reaction products of MPO, namely oxidation of cyanide by hypochlorous acid and reaction of thiocyanate with chloramines. Hypochlorous Acid myeloperoxidase Homo sapiens
2 In summary, our findings indicate that cyanide is a substrate for MPO and suggest an additional pathway for in vivo cyanate formation and protein carbamylation that involves MPO either directly or via its reaction products hypochlorous acid or chloramines. Hypochlorous Acid myeloperoxidase Homo sapiens