Title : Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats.

Pub. Date : 2018 May

PMID : 29488614






1 Functional Relationships(s)
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1 THS caused significant reductions in heart rate and mean arterial blood pressure, and was associated with significant increases in tumor necrosis factor-alpha, interleukin (IL)-6, IL-1beta, p-p38MAPK, NF-kappaB and AP-1 activation, in addition to TLR4 expression, in the lung. THYMIDINE-5'-(DITHIO)PHOSPHATE tumor necrosis factor Rattus norvegicus