Title : Bioresponsive Microneedles with a Sheath Structure for H2 O2 and pH Cascade-Triggered Insulin Delivery.

Pub. Date : 2018 Apr

PMID : 29479811






1 Functional Relationships(s)
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1 Herein, an H2 O2 -labile and positively charged amphiphilic diblock copolymer is synthesized, which is subsequently used to form nano-sized complex micelles (NCs) with insulin and glucose oxidase of pH-tunable negative charges. Hydrogen Peroxide insulin Homo sapiens