Title : Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.

Pub. Date : 1987 Jan

PMID : 2947954






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-Fluorodeoxyuridine (FUDR), a competitive inhibitor of thymidylate synthase, did cause an increase in the dUMP pool size indicating that this drug did not affect the synthesis of this substrate. Floxuridine thymidylate synthetase Homo sapiens
2 5-Fluorodeoxyuridine (FUDR), a competitive inhibitor of thymidylate synthase, did cause an increase in the dUMP pool size indicating that this drug did not affect the synthesis of this substrate. Floxuridine thymidylate synthetase Homo sapiens