Title : Testosterone complex and non-steroidal ligands of human aromatase.

Pub. Date : 2018 Jul

PMID : 29476820






2 Functional Relationships(s)
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1 Previously crystal structures of human AROM in complex with the substrate androstenedione, and inhibitors exemestane, as well as the newly designed steroidal compounds, have been reported. Androstenedione cytochrome P450 family 19 subfamily A member 1 Homo sapiens
2 Using five best X-ray data sets from androstenedione and testosterone complexes of AROM, we now unequivocally show the presence of an unexplained ligand electron density inside the proximal cavity. Androstenedione cytochrome P450 family 19 subfamily A member 1 Homo sapiens