Title : PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay.

Pub. Date : 2018 Apr 1

PMID : 29474549






1 Functional Relationships(s)
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1 PI3K/mTOR dual inhibitor LY3023414 showed activity at submicromolar concentration ranges against 13 of the 17 cell lines tested, including the ones with gemcitabine insensitivity. LY3023414 mechanistic target of rapamycin kinase Homo sapiens