Title : Cancer Imprints an Increased PARP-1 and p53-Dependent Resistance to Oxidative Stress on Lymphocytes of Patients That Later Develop Alzheimer's Disease.

Pub. Date : 2018

PMID : 29472838






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pharmacological inhibition of p53 increased lymphocyte survival in Ca&AD patients, contrary to the effect previously reported in HC and AD. Adenosine Monophosphate tumor protein p53 Homo sapiens
2 p53 inhibition showed a differential role in cancer and Ca&AD compared to HC and AD lymphocytes, that could explain the inverse susceptibility to oxidative death in cancer and AD. Adenosine Monophosphate tumor protein p53 Homo sapiens