Pub. Date : 2018 Jan 19
PMID : 29464059
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SDH loss leads to accumulation of intracellular succinate, which competitively inhibits dioxygenase enzymes, causing activation of pseudohypoxic signaling and hypermethylation of histones and DNA. | Succinic Acid | aminoadipate-semialdehyde synthase | Mus musculus |