Title : Simvastatin reduces adrenal catecholamine secretion evoked by stimulation of cholinergic nicotinic and angiotensinergic AT1 receptors.

Pub. Date : 2018 Mar

PMID : 29460135






2 Functional Relationships(s)
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1 In the presence of simvastatin, CA secretion evoked by 1.1-dimethyl-4-phenyl piperazinium iodide (DMPP), angiotensin II, high K+, veratridine, and Bay-K-8644 was time-dependently inhibited. Simvastatin angiotensinogen Rattus norvegicus
2 However, in the simultaneous presence of simvastatin and Nomega-nitro-L-arginine methyl ester hydrochloride, CA secretion evoked by angiotensin II and DMPP recovered to control levels. Simvastatin angiotensinogen Rattus norvegicus