Title : Vitamin D pathway genetic variants are able to influence sofosbuvir and its main metabolite pharmacokinetics in HCV mono-infected patients.

Pub. Date : 2018 Jun

PMID : 29452294






1 Functional Relationships(s)
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1 We evaluated the impact of polymorphisms in genes (CYP27B1, CYP24A1, VDBP and VDR) related to vitamin D pathway on sofosbuvir and GS-331007 plasma levels in HCV mono-infected patients at one month of treatment. Sofosbuvir GC vitamin D binding protein Homo sapiens