Pub. Date : 1986 Oct
PMID : 2944577
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We conclude that folinic acid stabilizes the effects of the fluoropyrimidines on thymidylate synthase of both mouse and human leukemic cell populations and that this enhancement is reflected in both inhibition of the growth of and the lethality to these cells. | fluoropyrimidines | thymidylate synthase | Mus musculus |
| 2 | We suggest that only doses of the fluoropyrimidines that are capable of initially inhibiting thymidylate synthase to a high degree will be synergistic with excess reduced folates. | fluoropyrimidines | thymidylate synthase | Mus musculus |