Pub. Date : 2018 May 5
PMID : 29438524
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Elevated Cyclic AMP Inhibits Mycobacterium tuberculosis-Stimulated T-cell IFN-gamma Secretion Through Type I Protein Kinase A. | Cyclic AMP | interferon gamma | Homo sapiens |
| 2 | We determined the levels of cAMP in peripheral blood mononuclear cells (PBMC) from tuberculosis patients and the mechanisms for cAMP suppression of IFN-gamma production. | Cyclic AMP | interferon gamma | Homo sapiens |
| 3 | PKA type I specific cAMP analogs inhibited Mtb-stimulated IFN-g production by PBMC through suppression of Mtb-induced IFN-gamma promoter binding activities of CREB, ATF-2, and c-Jun and also miR155, the target miRNA of these transcription factors. | Cyclic AMP | interferon gamma | Homo sapiens |