Title : Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.

Pub. Date : 2018 Apr

PMID : 29437575






2 Functional Relationships(s)
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1 APPROACH AND RESULTS: The treatment with SFAs, such as palmitic acid and stearic acid, promoted IL-1beta release in murine primary macrophages while treatment with oleic acid inhibited SFA-induced IL-1beta release in a dose-dependent manner. Palmitic Acid interleukin 1 beta Mus musculus
2 APPROACH AND RESULTS: The treatment with SFAs, such as palmitic acid and stearic acid, promoted IL-1beta release in murine primary macrophages while treatment with oleic acid inhibited SFA-induced IL-1beta release in a dose-dependent manner. Palmitic Acid interleukin 1 beta Mus musculus