Pub. Date : 2018 Apr
PMID : 29436639
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | GL inhibited the activation of the NF-kappaB and MAPK/ERK signaling pathways induced by HMGB1 and decreased the expression of monocyte chemoattractant protein-1 (MCP-1) and myeloid cell leukemia 1 (Mcl-1). | Glycyrrhizic Acid | mitogen-activated protein kinase 1 | Homo sapiens |
2 | Taken together, the results indicated that GL may suppress the migration of monocytes and induce apoptosis to reduce systemic inflammation by blocking downstream NF-kappaB/MCP-1 and MAPK/ERK/Mcl-1 signaling pathways. | Glycyrrhizic Acid | mitogen-activated protein kinase 1 | Homo sapiens |
3 | Taken together, the results indicated that GL may suppress the migration of monocytes and induce apoptosis to reduce systemic inflammation by blocking downstream NF-kappaB/MCP-1 and MAPK/ERK/Mcl-1 signaling pathways. | Glycyrrhizic Acid | mitogen-activated protein kinase 1 | Homo sapiens |