Pub. Date : 2018
PMID : 29427104
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SCA7 is pathomechanistically related to the group of CAG/polyglutamine (polyQ) expansion disorders, which includes other SCAs (1-3, 6 and 17), Huntington"s disease, spinal bulbar muscular atrophy and dentatorubro pallidoluysian atrophy. | polyglutamine | ataxin 7 | Homo sapiens |
| 2 | SCA7 is pathomechanistically related to the group of CAG/polyglutamine (polyQ) expansion disorders, which includes other SCAs (1-3, 6 and 17), Huntington"s disease, spinal bulbar muscular atrophy and dentatorubro pallidoluysian atrophy. | polyglutamine | ataxin 7 | Homo sapiens |
| 3 | The pathology is caused by an unstable CAG repeat expansion coding for a polyQ stretch in Ataxin-7 (ATXN7). | polyglutamine | ataxin 7 | Homo sapiens |
| 4 | The pathology is caused by an unstable CAG repeat expansion coding for a polyQ stretch in Ataxin-7 (ATXN7). | polyglutamine | ataxin 7 | Homo sapiens |
| 5 | PolyQ expansion in ATXN7 confers toxic properties and leads to selective neuronal degeneration in the cerebellum, the brain stem and the retina. | polyglutamine | ataxin 7 | Homo sapiens |