Title : Veterinary drug, 17β-trenbolone promotes the proliferation of human prostate cancer cell line through the Akt/AR signaling pathway.

Pub. Date : 2018 May

PMID : 29421751






2 Functional Relationships(s)
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1 When 22Rv1 cells were exposed to 30 pM of 17 TB, which is the effective concentration (EC50) value required to observe proliferative effects on 22Rv1 cells, the expression levels of the phosphorylated forms of Akt and GSK3beta were increased. Terbium AKT serine/threonine kinase 1 Homo sapiens
2 This study demonstrates that 17 TB induces AR-dependent proliferation through the modulation of cell cycle-related proteins in the Akt signaling pathway. Terbium AKT serine/threonine kinase 1 Homo sapiens