Title : Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis.

Pub. Date : 2018

PMID : 29408933






2 Functional Relationships(s)
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1 We tested four cre/ERT2 transgenes to allow tamoxifen-inducible removal of the LSL cassette and subsequent TPP1 expression at any stage of disease. Tamoxifen mitogen-activated protein kinase 3 Mus musculus
2 However, two of the cre/ERT2 driver transgenes had significant cre activity in the absence of tamoxifen, while cre-mediated recombination could not be induced by tamoxifen by two others. Tamoxifen mitogen-activated protein kinase 3 Mus musculus