Pub. Date : 2018 Jan
PMID : 29399562
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The immunoreactivity of phosphorylated ERK1/2 was elevated in cells treated with metformin, indicating the ERK1/2 signaling pathway in the neuroprotective effects of metformin in QUIN-induced cell death. | Metformin | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | The immunoreactivity of phosphorylated ERK1/2 was elevated in cells treated with metformin, indicating the ERK1/2 signaling pathway in the neuroprotective effects of metformin in QUIN-induced cell death. | Metformin | mitogen-activated protein kinase 3 | Homo sapiens |
| 3 | The immunoreactivity of phosphorylated ERK1/2 was elevated in cells treated with metformin, indicating the ERK1/2 signaling pathway in the neuroprotective effects of metformin in QUIN-induced cell death. | Metformin | mitogen-activated protein kinase 3 | Homo sapiens |
| 4 | The immunoreactivity of phosphorylated ERK1/2 was elevated in cells treated with metformin, indicating the ERK1/2 signaling pathway in the neuroprotective effects of metformin in QUIN-induced cell death. | Metformin | mitogen-activated protein kinase 3 | Homo sapiens |
| 5 | Collectively, our data demonstrates that metformin exerts its neuroprotective effects by inhibiting intracellular calcium increases, allowing it to regulate ERK1/2 signaling and modulate cell survival and death genes. | Metformin | mitogen-activated protein kinase 3 | Homo sapiens |