Title : Chlorinated Lipids Elicit Inflammatory Responses in vitro and in vivo.

Pub. Date : 2019 Jan

PMID : 29394241






1 Functional Relationships(s)
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1 Our data provide proof-of-principle that 2-ClPA and 2-ClHDA induce powerful proinflammatory responses both in vitro and in vivo, suggesting the possibility that these chlorinated lipid products of the MPO/ hydrogen peroxide /chloride system may contribute to inflammation noted in neutrophil-dependent, myeloperoxidase-mediated pathologic states such as ischemia/reperfusion, hemorrhagic shock, and sepsis. Chlorides myeloperoxidase Homo sapiens