Title : Dihydroisotanshinone I combined with radiation inhibits the migration ability of prostate cancer cells through DNA damage and CCL2 pathway.

Pub. Date : 2018 Jan 31

PMID : 29386061






4 Functional Relationships(s)
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Protein Name
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1 Dihydroisotanshinone I combined with radiation inhibits the migration ability of prostate cancer cells through DNA damage and CCL2 pathway. dihydroisotanshinone I C-C motif chemokine ligand 2 Homo sapiens
2 Mechanistically, DT and the combination treatment reduced the secretion of chemokine (C-C Motif) Ligand 2 (CCL2) from prostate cancer cells. dihydroisotanshinone I C-C motif chemokine ligand 2 Homo sapiens
3 Mechanistically, DT and the combination treatment reduced the secretion of chemokine (C-C Motif) Ligand 2 (CCL2) from prostate cancer cells. dihydroisotanshinone I C-C motif chemokine ligand 2 Homo sapiens
4 CONCLUSIONS: DT displays radiosensitization and antimigration effects in prostate cancer cells by inducing DNA damage and inhibiting CCL2 secretion. dihydroisotanshinone I C-C motif chemokine ligand 2 Homo sapiens