Pub. Date : 2018
PMID : 29385191
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effects of arecoline on proliferation of oral squamous cell carcinoma cells by dysregulating c-Myc and miR-22, directly targeting oncostatin M. | Arecoline | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
2 | Interestingly, c-myc promoter activity was also induced by arecoline. | Arecoline | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
3 | This result suggested the effect of arecoline to promote cell proliferation and cell-cycle progression of OSCC cells might be involved in induction of c-Myc expression and reduction of miR-22 resulting in OSM upregulation. | Arecoline | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |