Title : Effects of arecoline on proliferation of oral squamous cell carcinoma cells by dysregulating c-Myc and miR-22, directly targeting oncostatin M.

Pub. Date : 2018

PMID : 29385191






3 Functional Relationships(s)
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1 Effects of arecoline on proliferation of oral squamous cell carcinoma cells by dysregulating c-Myc and miR-22, directly targeting oncostatin M. Arecoline MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 Interestingly, c-myc promoter activity was also induced by arecoline. Arecoline MYC proto-oncogene, bHLH transcription factor Homo sapiens
3 This result suggested the effect of arecoline to promote cell proliferation and cell-cycle progression of OSCC cells might be involved in induction of c-Myc expression and reduction of miR-22 resulting in OSM upregulation. Arecoline MYC proto-oncogene, bHLH transcription factor Homo sapiens